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Single recipient cell tracking of tellurium-labeled extracellular vesicle proteomes (TeLEV) identifies EV-driven immunomodulation

2025-11-03

Abstract excerpt

Extracellular vesicles (EVs) mediate tumor-immune cell communication by carrying protein cargo that can immediately modulate signaling and antigen presentation. Yet mapping the uptake of primary EV proteomes by human immune cells at single-cell resolution has been constrained by a lack of labeling strategies. We show here that TeLEV, a tellurium-based metabolic mass tagging approach that incorporates L-2-tellurien...

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Identifiers and source

Literature Corpus work
07dc300d-0c2a-55ff-b988-d0db196669f8
DOI
10.1101/2025.11.01.685872
Open publication

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Single recipient cell tracking of tellurium-labeled extracellular vesicle proteomes (TeLEV) identifies EV-driven immunomodulationDOI 10.1101/2025.11.01.685872
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