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Matrix-Boosted Electrochemiluminescence Biosensor for Ultrasensitive Exosome Detection and Automated Phenotype Discrimination.

ACS sensors - 26 Jun 2026

Shi Yacheng, Wu Yang, Yan Zhiyong, Huang Hongjie, Liu Yang

Abstract excerpt

Accurate quantification and phenotypic discrimination of exosomes in complex biological fluids remain technically challenging sensing issues, yet they are essential for early cancer diagnosis. To address this challenge, an ultrasensitive electrochemiluminescence (ECL) biosensor is engineered by integrating a "matrix-boosted" Cp-Pt-Ti3-xC2Ty MXene emitter with a proximity-dependent "signal-off-on" aptamer...

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PMID: 42206473
DOI: 10.1021/acssensors.6c01482

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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