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Genetic variants and expression of the TIM-3 gene are associated with clinical prognosis in patients with epithelial ovarian cancer.

Gynecologic oncology - 1 Oct 2020

Wu Jian-Lei, Zhao Jian, Zhang Hai-Bo, Zuo Wei-Wei, Li Yan, Kang Shan

Abstract excerpt

OBJECTIVE: Polymorphisms of T cell immunoglobulin and mucin domain-containing molecule 3 (TIM-3) were reported to be associated with cancer risk and patients' survival. This study aims to investigate the correlation of TIM-3 polymorphisms with susceptibility to epithelial ovarian cancer (EOC) and patients' outcomes. METHODS: A total of 700 EOC patients and 710 healthy controls from North China were included. The...

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Identifiers

PMID: 32694063
DOI: 10.1016/j.ygyno.2020.07.012

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