Article
Unravelling the potential of TIM-3 gene polymorphism in allogeneic hematopoietic stem cell transplantation - a preliminary study.
Transplant immunology - 1 Aug 2024
Biały Sylwia, Siemaszko Jagoda, Sobczyk-Kruszelnicka Małgorzata, Fidyk Wojciech, Solarska Iwona, Nasiłowska-Adamska Barbara, Skowrońska Patrycja, Bieniaszewska Maria, Tomaszewska Agnieszka, Basak Grzegorz W, Giebel Sebastian, Wróbel Tomasz, Bogunia-Kubik Katarzyna
Abstract excerpt
BACKGROUND: T-cell immunoglobulin and mucin-domain containing-3 (TIM-3) molecule is a key regulator of the immune response by exerting an inhibitory effect on various types of immune cells. Understanding the role of TIM-3 in hematopoietic stem cell transplantation (HSCT) may improve transplant outcomes. Our study evaluated the potential association between TIM-3 polymorphisms, namely rs1036199 (A > C) or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
