Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TIM-3 Expression Level on AML Blasts Correlates With Presence of Core Binding Factor Translocations Rather Than Clinical Outcomes

14 Apr 2022

Abstract excerpt

Background T-cell immunoglobulin and mucin domain-containing molecule 3 (TIM-3) expresses on leukemic stem and progenitor populations of non-M3 acute myeloid leukemia (AML) as well as T lymphocytes. TIM-3 is thought to be involved in the self-renewal of leukemic stem cells and the immune escape of AML cells, however its correlation with AML prognosis is still controversial and worthy of further investigation....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Galectins and Cancer Biology
Share to Signaling Pathways in Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35494006
DOI: 10.3389/fonc.2022.879471

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TIM-3 Expression Level on AML Blasts Correlates With Presence of Core Binding Factor Translocations Rather Than Clinical OutcomesPMID 35494006Read ↗

Tim-3 is highly expressed in T cells in acute myeloid leukemia and associated with clinicopathological prognostic stratification.Semantic proximity Read ↗

Expression of immune check point gene TIM‑3 in patients newly diagnosed with acute myeloid leukemia: Significance and impact on outcomeSemantic proximity Read ↗

The correlation between Flt3-ITD mutation in dendritic cells with TIM-3 expression in acute myeloid leukemiaSemantic proximity Read ↗

Negative regulation of TIM-3 expression in AML cell line (HL-60) using miR-330-5pSemantic proximity Read ↗

[Molecular targeted therapy for acute myeloid leukemia].Semantic proximity Read ↗

NPM1 and DNMT3A mutations are associated with distinct blast immunophenotype in acute myeloid leukemia.Semantic proximity Read ↗

High IFITM3 expression predicts adverse prognosis in acute myeloid leukemiaSemantic proximity Read ↗

Associations between recurrent mutations and blast immunophenotype in acute myeloid leukemiaSemantic proximity Read ↗

IER3 (IEX-1) dysregulation serves as a potential prognostic factor in acute myeloid leukemia patients.Semantic proximity Read ↗

Ex vivo characterization of acute myeloid leukemia patients undergoing hypomethylating agents and venetoclax regimen reveals a venetoclax-specific effect on non-suppressive regulatory T cells and bona fide PD-1+TIM3+ exhausted CD8+ T cellsSemantic proximity Read ↗

Study on mechanism of Tim-3 on immune escape in benzene-induced acute myeloid leukemiaSemantic proximity Read ↗

High percentage of bone marrow CD8+ tissue-resident-like T cells predicts inferior survival in patients with acute myeloid leukemiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.