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Article

Endoplasmic reticulum aminopeptidases: biochemistry, physiology and pathology.

Journal of biochemistry - 1 Sept 2013

Hattori Akira, Tsujimoto Masafumi

Abstract excerpt

The human endoplasmic reticulum aminopeptidase (ERAP) 1 and 2 proteins were initially identified as homologues of human placental leucine aminopeptidase/insulin-regulated aminopeptidase. They are categorized as a unique class of proteases based on their subcellular localization on the luminal side of the endoplasmic reticulum. ERAPs play an important role in the N-terminal processing of the antigenic precursors...

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PMID: 23946506
DOI: 10.1093/jb/mvt066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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