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Article

Effects of genetically proxied lipid-lowering drugs on acute myocardial infarction: a drug-target mendelian randomization study.

Lipids in health and disease - 3 Jun 2024

Xiao Wendi, Li Yueying, Zhuang Zhenhuang, Song Zimin, Wang Wenxiu, Huang Ninghao, Dong Xue, Jia Jinzhu, Liu Zhonghua, Zhao Yimin, Qi Lu, Huang Tao

Abstract excerpt

OBJECTIVE: High low-density-lipoprotein (LDL) cholesterol has been associated with an increased risk of coronary artery diseases (CAD) including acute myocardial infarction (AMI). However, whether lipids lowering drug treatment is causally associated with decreased risk of AMI remains largely unknown. We used Mendelian randomization (MR) to evaluate the influence of genetic variation affecting the function of...

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Identifiers

PMID: 38831433
DOI: 10.1186/s12944-024-02133-w
PMCID: PMC11145822

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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