Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

SARS-CoV-2 in an immunocompromised host: convalescent plasma therapy and viral evolution elucidated by whole genome sequencing.

BMJ case reports - 9 Dec 2023

Seth-Smith Helena, Vesenbeckh Silvan, Egli Adrian, Ott Sebastian

Abstract excerpt

The evolution of SARS-CoV-2 within immunocompromised hosts who fail to clear the virus over many months has been proposed as a route to the development of Variants of Concern (VoCs). We present a case of an immunocompromised male patient with a prolonged SARS-CoV-2 infection. During hospitalisation, 7 weeks after first diagnosis, his condition worsened to require continuous ventilation support. Resolution of...

Topics

Humans
Male
SARS-CoV-2
COVID-19
COVID-19 Serotherapy
Immunization, Passive
Whole Genome Sequencing
Immunocompromised Host
Mutation
Genome, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 38087481
DOI: 10.1136/bcr-2023-255255
PMCID: PMC10728978

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2 in an immunocompromised host: convalescent plasma therapy and viral evolution elucidated by whole genome sequencing.PMID 38087481Read ↗

Cumulative SARS-CoV-2 mutations and corresponding changes in immunity in an immunocompromised patient indicate viral evolution within the host.Semantic proximity Read ↗

Case reports of persistent SARS-CoV-2 infection outline within-host viral evolution in immunocompromised patients.Semantic proximity Read ↗

SARS-CoV-2 intra-host evolution during prolonged infection in an immunocompromised patient.Semantic proximity Read ↗

Intra-host SARS-CoV-2 diversity in immunocompromised people living with HIV provides insight into the evolutionary trajectory of SARS-CoV-2.Semantic proximity Read ↗

SARS-CoV-2 population dynamics in immunocompetent individuals in a closed transmission chain shows genomic diversity over the course of infection.Semantic proximity Read ↗

SARS-CoV-2 intrahost evolution in immunocompromised patients in comparison with immunocompetent populations after treatment.Semantic proximity Read ↗

SARS-CoV-2 shedding, infectivity and evolution in an immunocompromised adult patientSemantic proximity Read ↗

Effect of molnupiravir on SARS-CoV-2 evolution in immunocompromised patients: a retrospective observational study.Semantic proximity Read ↗

Emergence of Multiple SARS-CoV-2 Antibody Escape Variants in an Immunocompromised Host Undergoing Convalescent Plasma Treatment.Semantic proximity Read ↗

Year-long COVID-19 infection reveals within-host evolution of SARS-CoV-2 in a patient with B cell depletionSemantic proximity Read ↗

Prolonged Infectious SARS-CoV-2 Shedding from an Immunocompromised PatientSemantic proximity Read ↗

SARS-CoV-2 Evolution and Immune Escape in Immunocompromised PatientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.