Article
Distinct functional neutrophil phenotypes in sepsis patients correlate with disease severity.
Frontiers in immunology - 1 Jan 2024
Yang Qingliang, Langston Jordan C, Prosniak Roman, Pettigrew Samantha, Zhao Huaqing, Perez Edwin, Edelmann Hannah, Mansoor Nadia, Merali Carmen, Merali Salim, Marchetti Nathaniel, Prabhakarpandian Balabhaskar, Kiani Mohammad F, Kilpatrick Laurie E
Abstract excerpt
Purpose: Sepsis is a clinical syndrome defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis is a highly heterogeneous syndrome with distinct phenotypes that impact immune function and response to infection. To develop targeted therapeutics, immunophenotyping is needed to identify distinct functional phenotypes of immune cells. In this study, we utilized our...
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