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LEUKOCYTE PHENOTYPING IN SEPSIS USING OMICS, FUNCTIONAL ANALYSIS, AND IN SILICO MODELING.

Shock (Augusta, Ga.) - 1 Feb 2023

Langston Jordan C, Yang Qingliang, Kiani Mohammad F, Kilpatrick Laurie E

Abstract excerpt

ABSTRACT: Sepsis is a major health issue and a leading cause of death in hospitals globally. The treatment of sepsis is largely supportive, and there are no therapeutics available that target the underlying pathophysiology of the disease. The development of therapeutics for the treatment of sepsis is hindered by the heterogeneous nature of the disease. The presence of multiple, distinct immune phenotypes ranging...

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Identifiers

PMID: 36377365
DOI: 10.1097/SHK.0000000000002047
PMCID: PMC9957940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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