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Article

P4HA2 involved in SLUG-associated EMT predicts poor prognosis of patients with KRAS-positive colorectal cancer.

Medical molecular morphology - 1 Sept 2024

El-Deek Heba El-Deek Mohammed, El-Naggar Maha Salah, Morsy Aiat Morsy Mohamed, Sedik Mayada Fawzy, Osman Heba Ahmed, Ahmed Asmaa M

Abstract excerpt

This study aimed to examine the immunohistochemical expression of epithelial-mesenchymal transition biomarkers: P4HA2 and SLUG in colorectal carcinoma (CRC) specimens, then to assess their relation to clinicopathological features including KRAS mutations and patients' survival, and finally to study the correlation between them in CRC. The result of this study showed that SLUG and P4HA2 were significantly higher...

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Identifiers

PMID: 38522060
DOI: 10.1007/s00795-024-00385-0
PMCID: PMC11343967

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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