Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The relationships of OSBPL3 expression with KI-67 expression and KRAS mutations in CRC: implications for diagnosis and prognosis.

BMC medical genomics - 14 Dec 2022

Zhang Min, Meng Lei, Zhang Zhaoxuan, Wu Jing, Chen Xi, Wang Yuejing, He Jie

Abstract excerpt

BACKGROUND: OSBPL3 is overexpressed in a variety of malignancies and is closely associated with tumor growth and metastasis. However, its expression and function in colorectal cancer (CRC) are unclear. We aimed to investigate its prognostic and therapeutic value in this disease by detecting its expression in CRC and its correlation with the clinicopathological characteristics and prognosis of patients. METHODS: A...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Neoplasms
Share to Fatty Acid-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ki-67 Antigen

Share to Mutation

Share to Prognosis

Share to Proto-Oncogene Proteins B-raf

Share to Proto-Oncogene Proteins p21(ras)

Source

Open in PubMed Open full text

Identifiers

PMID: 36517805
DOI: 10.1186/s12920-022-01402-w
PMCID: PMC9753258

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The relationships of OSBPL3 expression with KI-67 expression and KRAS mutations in CRC: implications for diagnosis and prognosis.PMID 36517805Read ↗

The respective relations of expression of OSBPL3 with Ki-67 expression and KRAS mutation in CRC for diagnosis and prognosisSemantic proximity Read ↗

The expression, immune infiltration, prognosis, and experimental validation of OSBPL family genes in liver cancerSemantic proximity Read ↗

OSBPL3 Regulates Colorectal Cancer Progression by Modulating Gut Microbiota and Tumor Immune MicroenvironmentSemantic proximity Read ↗

LINC02595 promotes tumor progression in colorectal cancer by inhibiting miR‐203b‐3p activity and facilitating BCL2L1 expressionSemantic proximity Read ↗

Oxysterol binding protein-like 3 (OSBPL3) is a novel driver gene that promotes tumor growth in part through R-Ras/Akt signaling in gastric cancerSemantic proximity Read ↗

CLK3 promotes tumor proliferation by activating MYC signalingSemantic proximity Read ↗

IGF2BP3 promotes progression of colorectal cancer and mediates cetuximab resistance by stabilizing EGFR mRNA in an m6A-dependent mechanismSemantic proximity Read ↗

GLI3 Promotes Invasion and Predicts Poor Prognosis in Colorectal CancerSemantic proximity Read ↗

CSF3 contributes to the invasive and metastatic phenotypes and associates with poor prognosis in patients with colorectal cancer via NF-κB signaling pathwaySemantic proximity Read ↗

Increased IGF2BP3 expression promotes the aggressive phenotypes of colorectal cancer cells in vitro and vivoSemantic proximity Read ↗

miR-133a-3p Functions as a Tumor Suppressor in Colorectal Cancer by Targeting PFKFB3Semantic proximity Read ↗

ORMDL1 is upregulated and associated with favorable outcome in colorectal cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.