Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of KRAS mutations and p53 expression on the postoperative prognosis of patients with colorectal cancer.

Molecular genetics & genomic medicine - 1 Jul 2022

Wang Lingfeng, Lin Shengtao, Yang Changshun, Cai Shaoxin, Li Weihua

Abstract excerpt

BACKGROUND: In the occurrence and development of colorectal cancer, p53 is an important regulator downstream of the MAPK signaling pathway and plays an important role in inhibiting abnormal proliferation signals generated by KRAS mutations. The purpose of this study is to explore the correlation between KRAS mutations and p53 expression and evaluate their prognosis values in colorectal cancer. METHODS: PCR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Proto-Oncogene Proteins p21(ras)

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 35686701
DOI: 10.1002/mgg3.1905
PMCID: PMC9266597

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of KRAS mutations and p53 expression on the postoperative prognosis of patients with colorectal cancer.PMID 35686701Read ↗

The association of clinicopathological features and survival in colorectal cancer patients with kras mutation status.Semantic proximity Read ↗

The impact of KRAS mutations on prognosis in surgically resected colorectal cancer patients with liver and lung metastases: a retrospective analysis.Semantic proximity Read ↗

KRAS gene mutations - prognostic factor in colorectal cancer?Semantic proximity Read ↗

The Prognostic Value of 18F-FDG PET/CT and KRAS Mutation in Colorectal CancersSemantic proximity Read ↗

RAS, BRAF, and TP53 gene mutations in Taiwanese colorectal cancer patients.Semantic proximity Read ↗

Differences in gene mutation profiles of colon cancer patients with or without a KRAS mutationSemantic proximity Read ↗

Prognostic significance of serum p53 antibody according to KRAS status in metastatic colorectal cancer patients.Semantic proximity Read ↗

Mutation patterns and prognostic analysis of BRAF/KRAS/PIK3CA in colorectal cancer.Semantic proximity Read ↗

The prognostic value of KRAS mutations in patients with colorectal cancer.Semantic proximity Read ↗

Prognostic Value of KRAS Gene Mutation on Survival of Patients with Peritoneal Metastases of Colorectal Adenocarcinoma.Semantic proximity Read ↗

P4HA2 involved in SLUG-associated EMT predicts poor prognosis of patients with KRAS-positive colorectal cancer.Semantic proximity Read ↗

Relationships among KRAS mutation status, expression of RAS pathway signaling molecules, and clinicopathological features and prognosis of patients with colorectal cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.