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Article

Organophosphate ester flame retardants and plasticizers affect the phenotype and function of HepG2 liver cells.

Toxicological sciences : an official journal of the Society of Toxicology - 28 May 2024

Yu Dongwei, Hales Barbara F, Robaire Bernard

Abstract excerpt

Exposure to the organophosphate esters (OPEs), used as flame retardants and plasticizers, is associated with a variety of adverse health effects including an increase in the incidence of fatty liver diseases. The goal of this study was to investigate the effects of six OPEs, all detected in Canadian house dust, on the phenotype and function of HepG2 liver cells. We used high-content imaging to investigate the...

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Identifiers

PMID: 38518089
DOI: 10.1093/toxsci/kfae034
PMCID: PMC11131028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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