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Article

Impact of Exposure to a Mixture of Organophosphate Esters on Adrenal Cell Phenotype, Lipidome, and Function.

Endocrinology - 20 Feb 2024

Li Zixuan, Hales Barbara F, Robaire Bernard

Abstract excerpt

Organophosphate esters (OPEs) are used primarily as flame retardants and plasticizers. Previously, we reported that adrenal cells are important targets of individual OPEs. However, real-life exposures are to complex mixtures of these chemicals. To address this, we exposed H295R human adrenal cells to varying dilutions (1/1000K to 1/3K) of a Canadian household dust-based OPE mixture for 48 hours and evaluated...

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Identifiers

PMID: 38376928
DOI: 10.1210/endocr/bqae024
PMCID: PMC10914377

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