Article
High-throughput functional genomics: A (myco)bacterial perspective.
Molecular microbiology - 1 Aug 2023
Winkler Kristy R, Mizrahi Valerie, Warner Digby F, De Wet Timothy J
Abstract excerpt
Advances in sequencing technologies have enabled unprecedented insights into bacterial genome composition and dynamics. However, the disconnect between the rapid acquisition of genomic data and the (much slower) confirmation of inferred genetic function threatens to widen unless techniques for fast, high-throughput functional validation can be applied at scale. This applies equally to Mycobacterium tuberculosis,...
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