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Article

Evaluating the frequency, prognosis and survival of RUNX1 and ASXL1 mutations in patients with acute myeloid leukaemia in northeastern Iran.

Journal of cellular and molecular medicine - 1 Jul 2022

Parsa-Kondelaji Mohammad, Ayatollahi Hossein, Rostami Mehrdad, Sheikhi Maryam, Barzegar Faezeh, Afzalaghaee Monnavar, Moradi Elmira, Sadeghian Mohammad Hadi, Momtazi-Borojeni Amir Abbas

Abstract excerpt

To evaluate the frequency and prognosis of runt-related transcription factor 1 (RUNX1) and additional sex combs like-1 (ASXL1) mutations in acute myeloid leukaemia (AML) patients in northeastern Iran. This cross-sectional study was performed on 40 patients with AML (including 35 patients with denovo AML and five patients with secondary AML) from February 2018 to February 2021. All patients were followed up for...

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PMID: 35692075
DOI: 10.1111/jcmm.17424
PMCID: PMC9258702

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