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Article

Copy number variant risk loci for schizophrenia converge on the BDNF pathway.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Apr 2024

Ehrhart Friederike, Silva Ana, Amelsvoort Therese van, von Scheibler Emma, Evelo Chris, Linden David E J

Abstract excerpt

OBJECTIVES: Schizophrenia genetics is intricate, with common and rare variants' contributions not fully understood. Certain copy number variations (CNVs) elevate risk, pivotal for understanding mental disorder models. Despite CNVs' genome-wide distribution and variable gene and protein effects, we must explore beyond affected genes to interaction partners and molecular pathways. METHODS: In this study, we...

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Identifiers

PMID: 38493363
DOI: 10.1080/15622975.2024.2327027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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