Article
Genome wide association studies (GWAS) and copy number variation (CNV) studies of the major psychoses: what have we learnt?
Neuroscience and biobehavioral reviews - 1 Jan 2012
Lee Kok Wei, Woon Puay San, Teo Yik Ying, Sim Kang
Abstract excerpt
Schizophrenia (SZ) and bipolar disorder (BPD) have high heritabilities and are clinically and genetically complex. Genome wide association studies (GWAS) and studies of copy number variations (CNV) in SZ and BPD have allowed probing of their underlying genetic risks. In this systematic review, we assess extant genetic signals from published GWAS and CNV studies of SZ and BPD up till March 2011. Risk genes...
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