Article
Psychiatric gene discoveries shape evidence on ADHD's biology.
Molecular psychiatry - 1 Sept 2016
Thapar A, Martin J, Mick E, Arias Vásquez A, Langley K, Scherer S W, Schachar R, Crosbie J, Williams N, Franke B, Elia J, Glessner J, Hakonarson H, Owen M J, Faraone S V, O'Donovan M C, Holmans P
Abstract excerpt
A strong motivation for undertaking psychiatric gene discovery studies is to provide novel insights into unknown biology. Although attention-deficit hyperactivity disorder (ADHD) is highly heritable, and large, rare copy number variants (CNVs) contribute to risk, little is known about its pathogenesis and it remains commonly misunderstood. We assembled and pooled five ADHD and control CNV data sets from the...
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