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Article

Clonal analysis of metachronous double biliary tract cancers.

The Journal of pathology - 1 May 2024

Omori Yuko, Aoki Shuichi, Ono Yusuke, Kokumai Takashi, Yoshimachi Shingo, Sato Hideaki, Kusaka Akiko, Iseki Masahiro, Douchi Daisuke, Miura Takayuki, Maeda Shimpei, Ishida Masaharu, Mizuma Masamichi, Nakagawa Kei, Mizukami Yusuke, Furukawa Toru, Unno Michiaki

Abstract excerpt

The molecular mechanisms underpinning the development of metachronous tumors in the remnant bile duct following surgical resection of primary biliary tract carcinomas (BTCs) are unknown. This study aimed to elucidate these mechanisms by evaluating the clinicopathologic features of BTCs, the alterations to 31 BTC-related genes on targeted sequencing, and the aberrant expression of p53, p16, SMAD4, ARID1A and...

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Identifiers

PMID: 38482714
DOI: 10.1002/path.6265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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