Article
Multigene mutational profiling of biliary tract cancer is related to the pattern of recurrence in surgically resected patients.
Updates in surgery - 1 Mar 2020
Conci Simone, Ruzzenente Andrea, Simbolo Michele, Bagante Fabio, Rusev Borislav, Isa Giulia, Lawlor Rita T, Pedrazzani Corrado, Iacono Calogero, Guglielmi Alfredo, Scarpa Aldo
Abstract excerpt
The aim of the present study was to investigate the relationship between the mutational gene profile and recurrence in biliary tract cancers (BTC). A total of 103 specimens of patients with BTC, who underwent curative surgery in a single tertiary HPB surgery referral center from 1990 to 2012, were assessed for mutational status in 52 cancer-related genes. Considering the different types of BTC, the 5-year...
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