Article
Identification of New Markers of Angiogenic Sprouting Using Transcriptomics: New Role for RND3.
Arteriosclerosis, thrombosis, and vascular biology - 1 May 2024
Abbey Colette A, Duran Camille L, Chen Zhishi, Chen Yanping, Roy Sukanya, Coffell Ashley, Sveeggen Timothy M, Chakraborty Sanjukta, Wells Gregg B, Chang Jiang, Bayless Kayla J
Abstract excerpt
BACKGROUND: New blood vessel formation requires endothelial cells to transition from a quiescent to an invasive phenotype. Transcriptional changes are vital for this switch, but a comprehensive genome-wide approach focused exclusively on endothelial cell sprout initiation has not been reported. METHODS: Using a model of human endothelial cell sprout initiation, we developed a protocol to physically separate cells...
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