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Article

The neuronal transcription factor NPAS4 is a strong inducer of sprouting angiogenesis and tip cell formation.

Cardiovascular research - 1 Feb 2017

Esser Jennifer Susanne, Charlet Anne, Schmidt Mei, Heck Sophia, Allen Anita, Lother Achim, Epting Daniel, Patterson Cam, Bode Christoph, Moser Martin

Abstract excerpt

RATIONALE: Regarding branching morphogenesis, neurogenesis and angiogenesis share common principle mechanisms and make use of the same molecules. Therefore, the investigation of neuronal molecules involved in vascular morphogenesis provides new possibilities for pro-angiogenic approaches in cardiovascular diseases. OBJECTIVE: In this study, we investigated the role of the neuronal transcription factor NPAS4 in...

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Identifiers

PMID: 28082451
DOI: 10.1093/cvr/cvw248

Genes

NPAS4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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