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Article

Activation of the NFκB signaling pathway in IL6+CSF3+ vascular endothelial cells promotes the formation of keloids

23 Aug 2022

Abstract excerpt

Background: Keloid is a disease caused by abnormal proliferation of skin fibres, the causative mechanism of which remains unclear. Method: In this study, endothelial cells of keloids were studied using scRNAseq combined with bulk-RNAseq data from keloids. The master regulators driving keloid development were identified by transcription factor enrichment analysis. The pattern of changes in vascular endothelial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36082167
DOI: 10.3389/fbioe.2022.917726

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