Transgenic Mice as a Model for Alzheimers Disease

Abstract excerpt

During the last few decades, numerous stable transgenic mouse strains have been developed in order to mimic a range of Alzheimers disease (AD)-related pathologies. Although none of the models fully replicates the human disease, the models have been a key feature in translational research, providing significant insights into the pathophysiology of AD. They have also been widely used in the preclinical testing of...

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