Article
Association between variants in TCF7L2, CTRB1/2, and GLP-1R genes and response to therapy with glucagon-like peptide-1 receptor agonists.
Postgraduate medicine - 1 Mar 2024
Kyriakidou Artemis, Kyriazou Angeliki V, Koufakis Theocharis, Vasilopoulos Yiannis, Avramidis Iakovos, Baltagiannis Stefanos, Goulis Dimitrios G, Kotsa Kalliopi
Abstract excerpt
OBJECTIVES: The factors determining the response to treatment with glucagon-like peptide-1 receptor agonists (GLP-1- RAs) have not been clarified. The present study investigated the association between polymorphisms in TCF7L2, CTRB1/2, and GLP-1 R genes and response to GLP-1 RAs regarding glycemic control and weight loss among Greek patients with type 2 diabetes mellitus (T2DM). METHODS: Patients (n = 191)...
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