Article

Pharmacogenomics of GLP-1 Receptor Agonists: A genome wide analysis of observational data and large randomized controlled trials

2022-05-30

Abstract excerpt

<h4>Summary</h4> <h4>Background</h4> In the treatment of type 2 diabetes (T2D), GLP-1 Receptor Agonists (GLP-1RA) lower glucose levels and body weight, and have cardiovascular benefits. GLP-1RA efficacy and side effects vary between people. Human pharmacogenomic studies of this inter-individual variation can provide both biological insight into drug action and provide biomarkers to inform clinical decision makin...

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Literature Corpus work: 4d63a159-4233-5d37-953f-c5a2decf33ef
DOI: 10.1101/2022.05.27.22271124

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