Article
Mendelian randomization study on causal association of FAM210B with drug-induced lupus.
Clinical rheumatology - 1 May 2024
Xu Yaqi, Gao Ran, Zhang Min, Zeng Qi, Zhou Shan, Zhu Gaizhi, Su Wenting, Wang Renxi
Abstract excerpt
OBJECTIVE: Due to the complexity of drug-induced lupus (DIL) pathogenesis, more susceptibility factors need to be discovered. FAM210B is a new mitochondrial protein whose function has not been fully elucidated. This study will explore whether there is a correlation between FAM210B and the risk of DIL. METHODS: At first, we extracted three FAM210B genetic variants from the GTEx database (n = 948), and extracted...
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