Article
Meta-analysis of FOXP3 polymorphisms and recurrent spontaneous abortion susceptibility.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Mar 2024
Shuai Ruzhen, Li Dandan, Xu Xincong, Yang Xiaojuan, Liu Dan
Abstract excerpt
BACKGROUND: The polymorphisms of the FOXP3 gene may mediate abnormalities in Tregs, leading to an imbalance in maternal-fetal immune tolerance and ultimately resulting in recurrent spontaneous abortion (RSA). This meta-analysis aims to assess the potential association between FOXP3 polymorphisms and susceptibility to RSA using five specific single nucleotide polymorphisms (SNPs). MATERIALS AND METHODS: By...
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