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Article

The synergic effects of CTLA-4/Foxp3-related genotypes and chromosomal aberrations on the risk of recurrent spontaneous abortion among a Chinese Han population.

Journal of human genetics - 1 May 2018

Fan Qin'e, Zhang Juanjuan, Cui Yu, Wang Chaoyun, Xie Yongjun, Wang Qiurong, Wu Libing

Abstract excerpt

The current study was aimed to investigate the association of CLTA-4/Foxp3 polymorphisms and chromosomal abnormalities with recurrent spontaneous abortion (RSA) risk in a Chinese Han population. Altogether, 1284 RSA women and 1046 women with normal pregnancy were incorporated in this study. The polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was implemented to genotype the...

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Source

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Identifiers

PMID: 29476189
DOI: 10.1038/s10038-018-0414-2
PMCID: PMC5915418

Genes

CLTA
CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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