Article
[Study on association of functional polymorphisms in Foxp3 gene with the susceptibility to unexplained recurrent spontaneous abortion].
Zhonghua fu chan ke za zhi - 1 Oct 2011
Wu Zai-gui, You Ze-shan, Zhang Cai, Li Zhu-yu, Su Xiu-mei, Zhang Xiu-ming, Li Yin-guang
Abstract excerpt
OBJECTIVE: To investigate the association between the functional polymorphisms of Foxp3 gene and unexplained recurrent spontaneous abortion (URSA). METHODS: PCR-restriction fragment length polymorphism (rs3761548, rs2294021) and PCR with sequence-specific primers (rs2232365, rs5902434) were used to detect four polymorphisms of Foxp3 in 146 URSA cases and 112 normal controls. RESULTS: (1) The frequencies of...
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