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Article

Association between functional polymorphisms of Foxp3 gene and the occurrence of unexplained recurrent spontaneous abortion in a Chinese Han population.

Clinical & developmental immunology - 1 Jan 2012

Wu Zaigui, You Zeshan, Zhang Cai, Li Zhuyu, Su Xiumei, Zhang Xiuming, Li Yinguang

Abstract excerpt

Unexplained recurrent spontaneous abortion (URSA) is an alloimmune disease associated with the failure of fetal-maternal immunologic tolerance in which the regulatory T lymphocytes (Treg) play a pivotal role. It is well known that Forkhead box P3 (Foxp3) is a crucial regulatory factor for the development and function of Treg cells. It has also been established that deficiency of the Foxp3 gene suppresses the...

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Identifiers

PMID: 21876709
DOI: 10.1155/2012/896458
PMCID: PMC3162971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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