Article
Association of Human forkhead box protein 3 (FOXP3) gene polymorphisms with idiopathic recurrent pregnancy loss among Kazakhstani women.
Gene - 30 Oct 2021
Abdukassimova Meruyert, Kanabekova Perizat, Bauyrzhanova Zhansaya, Ukybassova Talshyn, Kaldygulova Lyazzat, Imankulova Balkenzhe, Aimagambetova Gulzhanat, Almawi Wassim Y
Abstract excerpt
BACKGROUND: Recurrent pregnancy loss (RPL) is major pregnancy complication, with poorly defined cause.Forkhead Box P3 (FOXP3) is a transcription factor that supports Treg activation and development and attenuates immune responses. As FOXP3 production is genetically determined, we tested the association of FOXP3 gene variants with RPL. METHODS: A retrospective case-control study, performed between April 2019 and...
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