Article
Translocator protein/peripheral benzodiazepine receptor is not required for steroid hormone biosynthesis.
Endocrinology - 1 Jan 2014
Morohaku Kanako, Pelton Susanne H, Daugherty Daniel J, Butler W Ronald, Deng Wenbin, Selvaraj Vimal
Abstract excerpt
Molecular events that regulate cellular biosynthesis of steroid hormones have been a topic of intense research for more than half a century. It has been established that transport of cholesterol into the mitochondria forms the rate-limiting step in steroid hormone production. In current models, both the steroidogenic acute regulatory protein (StAR) and the translocator protein (TSPO) have been implicated to have...
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