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Article

Polymorphisms of IFN signaling genes and FOXP4 influence the severity of COVID-19.

BMC infectious diseases - 1 Mar 2024

Zhang Feng, Zhou Pingping, Wang Liangliang, Liao Xinzhong, Liu Xuejie, Ke Changwen, Wen Simin, Shu Yuelong

Abstract excerpt

BACKGROUND: The clinical manifestations of COVID-19 range from asymptomatic, mild to moderate, severe, and critical disease. Host genetic variants were recognized to affect the disease severity. However, the genetic landscape differs among various populations. Therefore, we explored the variants associated with COVID-19 severity in the Guangdong population. METHODS: A total of 314 subjects were selected, of which...

Topics

Humans
Male
Antibodies, Neutralizing
COVID-19
Forkhead Transcription Factors
Genotype
Haplotypes
Interferons
Polymorphism, Single Nucleotide
Myxovirus Resistance Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38429664
DOI: 10.1186/s12879-024-09040-6
PMCID: PMC10905836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-38429664-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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