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Article

The association of COVID-19 severity and susceptibility and genetic risk factors: A systematic review of the literature.

Gene - 20 Aug 2022

Ishak Angela, Mehendale Meghana, AlRawashdeh Mousa M, Sestacovschi Cristina, Sharath Medha, Pandav Krunal, Marzban Sima

Abstract excerpt

BACKGROUND: COVID-19 is associated with several risk factors such as distinct ethnicities (genetic ancestry), races, sexes, age, pre-existing comorbidities, smoking, and genetics. The authors aim to evaluate the correlation between variability in the host genetics and the severity and susceptibility towards COVID-19 in this study. METHODS: Following the PRISMA guidelines, we retrieved all the relevant articles...

Topics

COVID-19
Genetic Predisposition to Disease
Haplotypes
Humans
Polymorphism, Genetic
SARS-CoV-2

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 35714803
DOI: 10.1016/j.gene.2022.146674
PMCID: PMC9195407

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-35714803-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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