Article

Common Variants at 21q22.3 Locus Influence <i>MX1</i> Gene Expression and Susceptibility to Severe COVID-19

2021-01-20

Abstract excerpt

The COVID-19 disease, caused by the SARS-Cov-2, presents a heterogeneous clinical spectrum. The risk factors do not fully explain the wide spectrum of disease manifestations, so genetic factors could account for novel insights into its pathogenesis.In our previous study, we hypothesized that common variants on chromosome 21, near TMPRSS2 and MX1 genes, may be genetic risk factors associated with the different clin...

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Literature Corpus work: d192f1f4-5a26-5c56-a574-da30b5857836
DOI: 10.2139/ssrn.3770104

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