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A Chinese host genetic study discovered IFNs and causality of laboratory traits on COVID-19 severity

30 Sept 2021

Abstract excerpt

The COVID-19 pandemic has caused over 220 million infections and 4.5 million deaths worldwide. Current risk factor cannot fully explain the diversity in disease severity. Here, we present a comprehensive analysis of a broad range of patients' laboratory and clinical assessments to investigate the genetic contributions to COVID-19 severity. By performing GWAS analysis, we discovered several concrete associations...

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PMID: 34608450
DOI: 10.1016/j.isci.2021.103186

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