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Article

Characterisation and engineering of a thermophilic RNA ligase from Palaeococcus pacificus.

Nucleic acids research - 24 Apr 2024

Rousseau Meghan, Oulavallickal Tifany, Williamson Adele, Arcus Vic, Patrick Wayne M, Hicks Joanna

Abstract excerpt

RNA ligases are important enzymes in molecular biology and are highly useful for the manipulation and analysis of nucleic acids, including adapter ligation in next-generation sequencing of microRNAs. Thermophilic RNA ligases belonging to the RNA ligase 3 family are gaining attention for their use in molecular biology, for example a thermophilic RNA ligase from Methanobacterium thermoautotrophicum is commercially...

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PMID: 38421610
DOI: 10.1093/nar/gkae149
PMCID: PMC11040149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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