Article
Reconstitution and resonance assignments of yeast OST subunit Ost4 and its critical mutant Ost4V23D in liposomes by solid-state NMR.
Journal of biomolecular NMR - 1 Jun 2024
Chaudhary Bharat P, Struppe Jochem, Moktan Hem, Zoetewey David, Zhou Donghua H, Mohanty Smita
Abstract excerpt
N-linked glycosylation is an essential and highly conserved co- and post-translational protein modification in all domains of life. In humans, genetic defects in N-linked glycosylation pathways result in metabolic diseases collectively called Congenital Disorders of Glycosylation. In this modification reaction, a mannose rich oligosaccharide is transferred from a lipid-linked donor substrate to a specific...
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