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Article

Determination of the membrane topology of Ost4p and its subunit interactions in the oligosaccharyltransferase complex in Saccharomyces cerevisiae.

Proceedings of the National Academy of Sciences of the United States of America - 24 Jun 2003

Kim Hyun, Yan Qi, Von Heijne Gunnar, Caputo Gregory A, Lennarz William J

Abstract excerpt

Ost4p is a minimembrane protein containing only 36 amino acids and is a subunit of oligosaccharyltransferase (OT) in Saccharomyces cerevisiae. It was found previously when amino acid residues 18-25 of Ost4p were mutated to ionizable amino acids and defects were observed in the interaction between Ost4p and either Stt3p or Ost3p, two other components of OT. The transmembrane segment of Ost4p is likely to extend...

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Identifiers

PMID: 12810948
DOI: 10.1073/pnas.1332735100
PMCID: PMC164608

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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