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Article

Adult epithelioid glioblastoma exhibits an extremely poor prognosis and high frequency of SWI/SNF complex mutation: Insights from a retrospective study.

International journal of cancer - 1 Jul 2024

Xi Shaoyan, Jiang Shimeng, Li Hainan, Huang Qitao, Lu Jiabin, Zhang Xing, Li Zhi, Zeng Jing

Abstract excerpt

Epithelioid glioblastoma (eGBM) is a rare subtype of GBM. Given the update of the definition of GBM, the understanding of the molecular characteristics and prognosis of "true" adult eGBM remains limited. Herein, we retrospectively analyzed the clinicopathological data of 39 adult eGBM cases. Adult eGBM primarily affected females, with a male-to-female ratio of 1:2.3. The average age of diagnosis was 53 years, and...

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Source

Identifiers

PMID: 38411299
DOI: 10.1002/ijc.34854

Genes

ARID1B
BRAF
CDK4
CDKN2A
MGMT
TERT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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