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Article

Immunohistochemical and molecular genetic study on epithelioid glioblastoma: Series of seven cases with review of literature.

Pathology, research and practice - 1 May 2018

Khanna Gaurav, Pathak Pankaj, Suri Vaishali, Sharma Mehar Chand, Chaturvedi Sujata, Ahuja Arvind, Bhardwaj M, Garg Ajay, Sarkar Chitra, Sharma Rajeev

Abstract excerpt

Epithelioid glioblastoma (e-gbm) is a recently described variant of glioblastoma (GBM) which is associated with short survival and now added as a provisional entity to WHO 2016 classification of CNStumors. About half of these tumors show characteristic BRAF-V600E mutation. However, unlike conventional GBMs, e-gbm lack specific diagnostic and prognostic markers. Hence, we aimed to molecularly characterize these...

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PMID: 29615337
DOI: 10.1016/j.prp.2018.03.019

Genes

ATRX
BRAF
EGFR
GFAP
PTEN
TERT

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Immunohistochemical and molecular genetic study on epithelioid glioblastoma: Series of seven cases with review of literature.PMID 29615337Read ↗

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