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Article

The Significance of BRAF Mutation in the Epithelioid Glioblastoma Subtype: A Systematic Literature Review and a Case Report with a Unique Intraventricular Topography.

International journal of surgical pathology - 1 Jun 2024

Prieto Ruth, Barrios Laura, Ebrat-Mancilla Edwin, Martín Paloma, Tejerina Eva

Abstract excerpt

Epithelioid glioblastoma (E-GBM) is an exceedingly rare subtype of isocitrate dehydrogenase (IDH)-wildtype glioblastoma, first included in the WHO 2016 classification and characterized by a dominant population of epithelioid cells. Its histological and molecular defining features remain troublesome. The significance of BRAF mutations to pathological diagnosis and surgical outcome has drawn increasing attention...

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PMID: 37743598
DOI: 10.1177/10668969231195026

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