Article
Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium.
PloS one - 1 Jan 2013
Shah Tina, Engmann Jorgen, Dale Caroline, Shah Sonia, White Jon, Giambartolomei Claudia, McLachlan Stela, Zabaneh Delilah, Cavadino Alana, Finan Chris, Wong Andrew, Amuzu Antoinette, Ong Ken, Gaunt Tom, Holmes Michael V, Warren Helen, Swerdlow Daniel I, Davies Teri-Louise, Drenos Fotios, Cooper Jackie, Sofat Reecha, Caulfield Mark, Ebrahim Shah, Lawlor Debbie A, Talmud Philippa J, Humphries Steve E, Power Christine, Hypponen Elina, Richards Marcus, Hardy Rebecca, Kuh Diana, Wareham Nicholas, Langenberg Claudia, Ben-Shlomo Yoav, Day Ian N, Whincup Peter, Morris Richard, Strachan Mark W J, Price Jacqueline, Kumari Meena, Kivimaki Mika, Plagnol Vincent, Dudbridge Frank, Whittaker John C, Casas Juan P, Hingorani Aroon D
Abstract excerpt
Substantial advances have been made in identifying common genetic variants influencing cardiometabolic traits and disease outcomes through genome wide association studies. Nevertheless, gaps in knowledge remain and new questions have arisen regarding the population relevance, mechanisms, and appl...
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