Article
Intensive lifestyle intervention in type 2 diabetes and risk of incident coronary artery disease for the common haptoglobin phenotypes: the Look AHEAD study.
Cardiovascular diabetology - 24 Feb 2024
Warren Rachel A, Bancks Michael P, Carew Allie S, Levy Andrew P, Sapp John, Bahnson Judy, Lewis Cora E, Rimm Eric B, Espeland Mark A, Cahill Leah E
Abstract excerpt
BACKGROUND: Intensive glycemic control reduced coronary artery disease (CAD) events among the Action to Control Cardiovascular Disease Risk in Diabetes (ACCORD) participants with the haptoglobin (Hp) 2-2 phenotype only. It remains unknown whether Hp phenotype modifies the effect of an intensive lifestyle intervention (ILI) on CAD in type 2 diabetes. METHODS: Haptoglobin phenotype was measured in 4542 samples from...
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