Article
The relationship between repeated measurements of HbA1c and risk of coronary events among the common haptoglobin phenotype groups: the Action for Health in Diabetes (Look AHEAD) study.
Cardiovascular diabetology - 9 Oct 2024
Carew A S, Warren R A, Bancks M P, Espeland M A, Bahnson J L, Lewis C L, Levy A P, Sapp J L, Urquhart R, Wang J L, Rimm E B, Cahill L E
Abstract excerpt
BACKGROUND: In the ACCORD study, participants with the haptoglobin (Hp) 2-2 phenotype and glycated hemoglobin (HbA1c) ≥ 8.0% had a higher risk of coronary artery disease (CAD) compared to those with HbA1c 7.0-7.9%. However, this association was not observed in participants without the Hp2-2 phenotype. The optimal glycemic target for CAD prevention for the Hp phenotypes remains uncertain and may vary based on...
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