Article
Haptoglobin genotype: a determinant of cardiovascular complication risk in type 1 diabetes.
Diabetes - 1 Jun 2008
Costacou Tina, Ferrell Robert E, Orchard Trevor J
Abstract excerpt
OBJECTIVE: Haptoglobin is a plasma protein that binds free hemoglobin, thereby inhibiting hemoglobin-induced oxidative damage. We investigated the association between the haptoglobin genotype and the incidence of coronary artery disease (CAD) in a cohort of individuals with childhood-onset type 1 diabetes. RESEARCH DESIGN AND METHODS: Participants from the Epidemiology of Diabetes Complications Study who were...
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