Article
PlentiPlex™ MYD88 Waldenström lymphoma qPCR assay: A highly sensitive method for detection of MYD88 L265P mutation.
International journal of laboratory hematology - 1 Aug 2024
Viscovo Marcello, Clemmensen Mia de Laurent, Fosso Federica, Maiolo Elena, Autore Francesco, Laurenti Luca, Hohaus Stefan, Chiusolo Patrizia
Abstract excerpt
INTRODUCTION: Agarose gel-based conventional and real-time allele-specific polymerase chain reaction (AS-PCR) assays are currently used for sensitive detection and quantification of MYD88 L265P mutation. Visual inspection of an agarose gel can often be ambiguous. We propose a new allele-specific quantification PCR (AS-qPCR) assay, PlentiPlex™ MYD88 Waldenström lymphoma qPCR assay, that uses Intercalating Nucleic...
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